منابع مشابه
Severe selective IgM deficiency.
Among the primary antibody deficiency syndromes, severe selective IgM deficiency (also previously known as type V dysgammaglobulinaemia) is rare, and the majority of previous reports have indicated a fatal outcome. Three adult patients who were found to have a persistently low serum IgM are described. This deficiency was not obviously related to their presenting illness; in two of the patients,...
متن کاملSelective IgM Deficiency—An Underestimated Primary Immunodeficiency
Although selective IgM deficiency (SIGMD) was described almost five decades ago, it was largely ignored as a primary immunodeficiency. SIGMD is defined as serum IgM levels below two SD of mean with normal serum IgG and IgA. It appears to be more common than originally realized. SIGMD is observed in both children and adults. Patients with SIGMD may be asymptomatic; however, approximately 80% of ...
متن کاملSelective IgM deficiency: a case study.
We experienced an 85-year-old male patient with selective IgM deficiency. The average levels of his serum immunoglobulins were as follows: IgG, 1,165 mg/dl, IgA 280 mg/dl, and IgM 17 mg/dl. The subpopulations of peripheral blood lymphocytes in this patient were normal, including normal numbers of IgM-bearing lymphocytes. Normal amounts of cells with cytoplasmic IgM were induced by in vitro addi...
متن کاملPseudomonas septicemia in selective IgM deficiency.
pyogenic meningitis, however, CSF culture was sterile. Gram stain of CSF and skin lesions revealed no bacteria. Culture of fluid from skin lesions, blood culture and ear discharge grew Pseudomonas aeruginosa. Serum IgG level was 930 mg/dL, IgA was 102 mg/dL, and IgM was 12 mg/dL. Serum IgM level of father was. 19.5 mg/dL. The patient was administered appropriate antibiotics, platelet transfusio...
متن کاملSyndrome of selective IgM deficiency with severe T cell deficiency associated with disseminated cutaneous mycobacterium avium intracellulaire infection.
Cutaneous non-disseminated, non-tuberculous mycobacterial infections have been reported in both immunocompetent and immunocompromised subjects. Systemic Mycobacterium avium intracellulaire (MAI) have been reported in non-HIV patients with Idiopathic CD4 lymphocytopenia. We report a comprehensive immunological analysis in syndrome of selective IgM deficiency and T lymphocytopenia (both CD4+ and ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1976
ISSN: 0021-9746
DOI: 10.1136/jcp.29.9.773